Table 6 Classification of antibacterial drugs frequently used in the treatment of enteric colibacillosis according to pharmacokinetics and pharmacodynamics indices (modified from Ahmad et al. [41])
From: Swine enteric colibacillosis: diagnosis, therapy and antimicrobial resistance
| Drugs | Bacterial effect | PK/PD parameters |
|---|---|---|
| Fluoroquinolones (enrofloxacin) | Concentration dependent | Cmax/MIC and AUC/MIC |
| Cephalosporins (ceftiofur) | Time dependent | T > MIC |
| Sulphonamides + Diaminopyrimidines (trimethoprim + sulfamethoxazole) | Time dependent | T > MIC |
| Aminoglycosides (neomycin) | Concentration dependent | Cmax/MIC or AUC/MIC |
| Aminocyclitols (spectinomycin) | T > MIC | |
| Polymyxins (colistin) | Concentration dependent | AUC/MIC |